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doi: 10.1111/j.1365-313X.2008.03447.x 58 WangwattanaB.KoyamaY.NishiyamaY.KitayamaM.SaitoK

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Signals from dural perivascular neurons instigate a sequence of events that lead to the release of inflammatory mediators, sterile meningeal inflammation, and sensitization of pain-processing brain regions (33)