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Thirdly, this reagent, as a powder is more stable, and can be stored at room temperature in brown glass bottle, while CMQT and CMLT require to be kept in darkness at 4 C

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Proposed Mechanisms Preventing GABA receptor downregulation Counteracting compensatory NMDA glutamate receptor sensitization Stabilizing benzodiazepine receptor configuration (preventing shift to inverse agonist state) Upregulating GABAergic neurotransmission through pathways distinct from benzodiazepine action itself This tolerance prevention has profound clinical implications