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But when your cellular systems become strained, even small additional exposures can trigger system-wide stress responses that show up as chemical sensitivity symptoms

Resynthesis of GSH from the oxidized form is catalyzed by glutathione reductase, where the necessary NADPH + +H + is produced in pentose pathway of carbohydrates [36]

The above calculation is obviously simplistic as the rates of the two reactions will vary as a function of changes in substrate concentrations following the onset of stress, and kinetic modeling would be required to examine the question more closely