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As a typical damage-associated molecular pattern (DAMP) molecule, HMGB1 can mediate heat stress-induced NLRP3 inflammasome activation via the TLR4 and receptor for advanced glycation end products (RAGE) signaling pathways, thereby promoting IL-1 activation and inducing hepatocyte pyroptosis, ultimately leading to severe liver injury in rats [26]

Some of the allyl compounds in the essential oil of garlic are diallyl sulphide, DATS, DADS, and diallyl polysulfides, which exhibit antioxidant effects (Santhosha et al., 2013)

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Its crucial to consult with Mexico healthcare professionals or research supervisors to evaluate the synergy and safety of these combinations in specific contexts