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187 In head and neck squamous cell carcinoma (HNSCC), phosphorylated STAT3 can directly bind to the ARG1 promoter region of MDSCs to promote transcription, thereby contributing to the immunosuppressive effect of MDSCs

PubMed record Dadzie OE, et al

c , Illustration of the TMEFF1-C peptide consisting of the HIV1 TAT cell-penetrating peptide fused to the peptide corresponding to the cytoplasmic domain of TMEFF1

NO influences protein kinase B (Akt) signaling though a cGMP/phosphoinositide 3-kinase (PI3K) dependent pathway, which is the primary pathway for upregulating translation initiation required for muscle protein synthesis