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En estudios clnicos cosmticos las concentraciones efectivas van de 0.05% (500 ppm) a 0.5% (5,000 ppm)

Hence, contrary to the expectation that hematopoietic progenitors would be geno-protected throughout life, we found that progenitor cells from aged killifish carry higher levels of DNA damage compared to all other cell types in the hematopoietic organ, as recently shown in aged mammalian HSCs 77,78 , and to some extent, in aged-adult humans 79