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The 2013 paper by McCoy et al

Although the particular reason for the increased incidence of male infertility remains elusive, various environmental, nutritional and socioeconomic factors have been suggested to contribute to the downward trend in semen quality (10, 11)

Abstract Increasing evidence suggests that renal inflammation contributes to the pathogenesis and progression of diabetic kidney disease (DKD) and that anti-inflammatory therapies might have renoprotective effects in DKD