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While it is far more stable at room temperature than the acetate version, refrigeration is still the best practice for preserving maximum potency and integrity for the duration of your research project

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What unopened bac water looks like across its labeled life For sealed, unpunctured bottles, the labeled expiration date (typically 18-24 months from manufacture) is the governing window

Watch for worsening pain and spreading redness beyond the immediate area after 48 to 72 hours, fever, a hard warm lump, or systemic allergic symptoms such as hives, facial swelling, throat tightness, or breathing difficulty