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Overexpression of nuclear receptor subfamily 1, group D member 1 (NR1D1)/Rev-Erba, an orphan nuclear receptor, has been shown to enhance the antimycobacterial properties of macrophages and decrease the survival of M.tb by promoting phagosomelysosome maturation through IL-10 repression in human macrophages[53]

This approach holds significant value in facilitating the development of more precise and personalized treatment plans, thereby enhancing the prognosis of tumor patients

Depleting GSH levels can exert detrimental effects on cancer cells, potentially augmenting the efficacy of chemotherapy and ionizing radiation treatments [211]

After oral administration of senkyunolide I (36 mg/kg), the parent compound and nine metabolites were identified in rat bile (109)