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doi: 10.3389/fcell.2025.1737456 Received 01 November 2025 Revised 14 December 2025 Accepted 22 December 2025 Published 12 January 2026 Volume 13 - 2025 Edited by Silvia Masciarelli, Sapienza University of Rome, Italy Reviewed by Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Weibei Sheng, Peking University, China Updates Copyright 2026 Zhang, Li, Yang and Yang

NAD+ is the exception its sting is acidity-driven, so NaCl helps only the osmotic part and buffering the pH helps more. How does injection site affect repair-peptide distribution, and does proximity to an injury matter

Long R3 IGF-1 bioactivity and reduced IGFBP affinity Bach et al

In healthy adults, its activity declines with age, contributing to the progressive loss of synaptic density and cognitive flexibility that most people experience starting in their 40s and 50s