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490 Excessive inhibition of Nrf2 may not improve DOX-induced cardiomyopathy due to insufficient promotion of antioxidant gene expression, while its overactivation increases the breakdown of heme and ferrous iron levels in the HO-1-catalyzed manner, promoting ferroptosis

doi: 10.1016/j.biopsych.2021.05.008, 40

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doi:10.1590/S1516-89132013000500017 Ask M, Mapelli V, Hck H, Olsson L, Bettiga M (2013) Engineering glutathione biosynthesis of Saccharomyces cerevisiae increases robustness to inhibitors in pretreated lignocellulosic materials