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Diluent: The liquid you'll use for reconstitution

Concurrent application with highly acidic or strongly chelating topical agents-such as concentrated ascorbic-acid serums-may reduce the activity of one or both products because copper ions can catalyze oxidation reactions

That is a real risk arguably a greater one than the theoretical risks the FDA cited when it enacted the 2023 restrictions

The nominations for KPV were submitted by the Wells Pharmacy Network and LDT Health Solutions on behalf of the International Peptide Society and then withdrawn by the nominators, leaving the FDA to proceed with the review on its own initiative