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Studies have revealed that hyperglycemia stimulates a reversible increase in the concentrations of IL-6 and decline in histone-3 methylation at the IL-6 promoter in cardiomyocytes [200]

Hoffman, R

At the time of writing, the FDA has so far noted an absence of safety concerns based on their review to date and is considering exercising enforcement discretion regarding the sale and distribution of (at least some) NAC-containing supplement products

However, if youre supplementing with this vitamin, you can minimize your risk of getting too much by taking no more than 90 mg per day if youre a man or 75 mg per day if youre a woman