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Primary sclerosing cholangitis: the multifocal short biliary strictures and upstream dilatation result in the characteristic appearance of beads on a string

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Other Symptoms & Complications Headache Memory and learning problems Depression and anxiety Raynauds syndrome, in which the fingers turn white or blue from cold Swelling in the eyes, hands, legs and feet Small red spots, sores, damaged veins or calcium deposits under the skin Hair loss Ulcers in the nose, mouth or genitals Weakened nerves in the arms and legs Anemia or abnormal blood clotting Kidney disease and failure Heart disease Seizures and stroke Increased risk of infection, cancer, bone tissue loss and pregnancy complications (x, x, x) Though males and females manifest the same general symptoms, some symptoms may differ between them

Chemical reprogramming for cell fate manipulation: methods, applications, and perspectives