You should not take cyanocobalamin-based products if you: Have a known cobalt allergy Have Lebers hereditary optic neuropathy , as B12 can worsen vision in this condition Discuss nasal B12 with your clinician first if you have: Severe megaloblastic anemia Polycythemia vera or other bone marrow disorders Low iron or folate Kidney disease Are undergoing chemotherapy or using bone marrowsuppressing drugs Are pregnant or breastfeeding Possible Side Effects Most side effects reported with B12 nasal products are mild and temporary: Slight nasal irritation, burning, or dryness Runny or stuffy nose, sneezing, or sore throat Mild headache Nausea or a brief metallic taste Tingling or pins and needles sensations, especially early on as nerves recover Serious reactions are rare but require immediate medical care: Rash, hives, or intense itching Swelling of the face, lips, tongue, or throat Trouble breathing or swallowing Fever, chills, or signs of infection that dont match a simple cold If anything feels out of proportion or youre unsure, stop the product and speak with your healthcare provider or seek urgent care
The concern about kidney load is more commonly associated with peptides that stimulate significant systemic hormone production or with impurities in research-grade sources
This led us to a debate about how, when you know a bit more about B12 deficiency and Pernicious Anaemia than your GP surgery, it comes as a bit of a surprise when bureaucracy outweighs common sense
Combination protocol: BPC-157 300-500mcg daily plus TB-500 2.5-5mg twice weekly for 6-8 weeks (loading), then BPC-157 maintenance 200-300mcg daily another 4-8 weeks
