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In diabetic rats, which are known to exhibit severely delayed wound healing, PIC treatment demonstrated elevated glutathione and ascorbic acid levels, improved epithelialization, and enhanced activation of fibroblasts and mast cells in the wound area

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In a chronic stress model, morin treatment improved levels of key neurotransmitters (epinephrine, norepinephrine, and 5-HT) and reduced inflammatory markers including tumor necrosis factor-alpha, toll-like receptor-4, NOD-like receptor pyrin domain-containing protein-3, interleukin-1beta, and caspase-1 levels, as well as the status of the critical apoptotic marker, caspase-3 in the brain