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This important preclinical study showed that ketamine and other NMDAR antagonists produce fast-acting antidepressant-like effects in mouse models that depend on the rapid synthesis of BDNF via a mechanism that includes the deactivation of eEF2 kinase

Mller A, Gabriel H, Sies H (1985) A novel biologically active selenoorganic compoundIV: protective glutathione-dependent effect of PZ 51 (Ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes

Access this article Similar content being viewed by others Abbreviations -ECS: -Glutamylcysteine synthetase ABA: Abscisic acid APX: Ascorbate peroxidase AsA: Ascorbate CAT: Catalase Cys: Cysteine DHAR: Dehydroxyascorbate reductase Glu: Glutamine Gly I: Glyoxalase I (Lactoylglutathione lyase) Gly II: Glyoxalase II (Hydroxyacylglutathione hydrolase) GPX: Glutathione peroxidase GR: Glutathione reductase GSH: Glutathione GSHS: Glutathione synthase GSNO: S -Nitrosoglutathione GSSG: Glutathione disulfide GST: Glutathione S -transferase JA: Jasmonic acid MAP: Mitogen activated protein MDA: Malondialdehyde MG: Methylglyoxal NADPH: Nicotinamide adenine dinucleotide phosphate NO: Nitric oxide PC: Phytochelatin PCS: Phytochelatin synthase POD: Peroxidase ROS: Reactive oxygen species SA: Salicylic acid SLG: S -d-Lactoylglutathione SOD: Superoxide dismutase References Akter N, Sobahan MA, Uraji M, Ye W, Hossain MA, Mori IC, Nakamura Y, Murata Y (2012) Effects of depletion of glutathione on abscisic acid- and methyl jasmonate-induced stomatal closure in Arabidopsis thaliana