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Recent studies have also shown that SAM can act as a therapeutic agent for treating depression, as an antidepressant in Parkinsons disease, and in endogenous and bipolar patients with depression and hypomanic symptoms (67)

(1996) compared globular (native and molten globular) and non-globular states (unfolded protein and randomly coiled, partially -helical, and partially -structural synthetic polypeptides) of several proteins and model polypeptides using Guinier (used for the R g evaluation) and Kratky plots, as well as analyzed the globularization process in protein folding using the integrated SAXS intensity (Semisotnov et al., 1996)