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Basic & Clin

10.1016/j.jacc.2021.03.003 20 D'AvinoD.CerquaI.UllahH.SpinelliM.Di MatteoR.GranatoE.et al (2023)

Add-back therapy with norethindrone acetate is recommended to avoid serious long-term sequelae (36)

This decrease contributes to various age-related issues, including cognitive decline, decreased energy production, and increased oxidative stress, making supplementation potentially beneficial for older adults.